2024
Stress and Parental behaviors (Review)
Wang, Y., Lin, D.
Neuroscience Research. 2024 Dec 12. [link]
Leptin-activated hypothalamic BNC2 neurons acutely suppress food intake
Tan, H.L., Yin, L., Tan, Y., Ivanov, J., Plucinska, K., Ilanges, A., Herb, B.R., Wang, P., Kosse, C., Cohen, P., Lin, D., Friedman, J.M.
Nature. 2024 October 30 [link]
The multi-stage plasticity in the aggression circuit underlying the winner effect
Yan, R., Wei, D., Varshneya, A., Shan, L., Dai, B., Asencio III, H.J., Gollamudi, A., Lin, D.
Cell. 2024 October 14 [link] [Raw Data] [BioRxiv version]
Chen, Y., Chien, J., Dai, B., Lin, D., Chen ZS.
Journal of Neural Engineering, 2024 [link] [BioRxiv version]
Monitoring norepinephrine release in vivo using next-generation GRABNE sensors
Feng, J., Dong, H., Lischinsky, J.E., Zhou J., Deng F., Zhuang C., Miao X., Wang H., Li G., Cai R., Xie H., Cui G., Lin, D., Li, Y.
Neuron. 2024 Mar 27. [link] [BioRxiv version]
Brain-wide multi-fiber recording of neuronal activity in freely moving mice
Dai B., Guo Z., Lin, D.
STAR Protocols. 2024 Mar 15. [link]
A dedicated hypothalamic oxytocin circuit controls aversive social learning
Osakada, T., Yan, R., Jiang Y., Wei, D., Tabuchi, R., Dai B., Wang, X., Zhao, G., Wang, C.X., Liu, J.J., Tsien, R.W., Mar, A.C., Lin, D.
Nature. 2024 Jan 24. [link][BioRxiv version][Raw data]
2023
A toolkit of highly selective and sensitive genetically encoded neuropeptide sensors
Wang H., Qian T., Zhao Y., Zhuo Y., Wu C., Osakada T., Chen P., Chen Z., Ren H., Yan Y., Geng L., Fu S., Mei L., Li G., Wu L., Jiang Y., Qian W., Zhang L., Peng W., Xu M., Hu J., Jiang M., Chen L., Tang C., Zhu Y., Lin D., Zhou J.N., Li Y.
Science. 2023 Nov 17. [link][BioRxiv version]
Transcriptionally defined amygdala subpopulations play distinct roles in innate social behaviors
Lischinsky, J., Yin, L., Shi, C., Prakash, N., Burke, J., Shekaran, G., Grba, M., Corbin, J.G., Lin, D.
Nature Neuroscience. 2023 Nov 09. [PDF][BioRxiv version][Raw data]
Hypothalamic control of innate social behaviors (Review)
Mei, L., Osakada,T., Lin, D.
Science. 2023 Oct 26. [PDF]
Neural dynamics in the limbic system during male social behaviors
Guo, Z., Yin, L., Diaz, V., Dai,B., Osakada,T., Lischinsky, J.E., Chien, J., Yamaguchi, T., Urtecho, A., Tong, X., Chen, Z.S., Lin, D.
Neuron. 2023 Aug 15. [PDF] [BioRxiv version][Raw data]
Antagonistic circuits mediating infanticide and maternal care in female mice
Mei, L., Yan, R., Yin, L., Sullivan, R.M., Lin, D.
Nature. 2023 Jun 07. [PDF] [BioRxiv version][Raw data]
A hypothalamic pathway that suppresses aggression toward superior opponents
Wei, D., Osakada, T., Guo, Z., Yamaguchi, T., Varshneya, A., Yan, R., Jiang, Y., Lin, D.
Nature Neuroscience. 2023 Apr 10. [PDF][Raw data]
Neural control of female sexual behaviors (Review)
Yin, L., Lin, D.
Hormones and Behavior. 2023 Mar 04. [PDF]
A genetically encoded sensor measures temporal oxytocin release from different neuronal compartments
Qian, T., Wang, H., Wang, P., Geng, L., Mei, L., Osakada, T., Wang, L., Tang, Y., Kania, A., Grinevich, V., Stoop, R., Lin, D., Luo, M., Li, Y.
Nature Biotechnology. 2023 Jan 02. [PDF] [BioRxiv version]
2022
Responses and functions of dopamine in nucleus accumbens core during social behaviors
Dai, B., Sun, F., Tong. X., Ding, Y., Kuang, A., Osakada, T., Li, Y., Lin, D.
Cell Reports. 2022 Aug 23. [PDF] [Supplement] [BioRxiv version]
VMHvllCckar cells dynamically control female sexual behaviors over the reproductive cycle
Yin, L., Hashikawa, K., Hashikawa, Y., Osakada, T., Lischinsky, J.E., Diaz, V., Lin, D.
Neuron. 2022 Jul 26. [PDF][Supplement]
Pushing the frontiers: tools for monitoring neurotransmitters and neuromodulators (Review)
Wu, Z., Lin, D., Li, Y.
Nature Reviews Neuroscience. 2022 Mar 31. [PDF]
2021
Oxytocin neurons enable social transmission of maternal behaviour
Carcea, I., Caraballo, N.L., Marlin, B.J., Ooyama, R., Riceberg, J.S., Mendoza Navarro, J.M., Opendak, M., Diaz, V.E., Schuster, L., Alvarado Torres, M.I., Lethin, H., Ramos, D., Minder, J., Mendoza, S.L., Bair-Marshall, C.J., Samadjopoulos, G.H., Hidema, S., Falkner, A., Lin, D., Mar, A., Wadghiri, Y.Z., Nishimori, K., Kikusui, T., Mogi, K., Sullivan, R.M., Froemke, R.C.
Nature. 2021 Aug 11. [PDF] [BioRxiv version]
Neural circuits of social behaviors: innate yet flexible (Review)
Wei, D., Talwar, V., Lin, D.
Neuron. 2021 Mar 10. [PDF]
2020
Next-generation GRAB sensors for monitoring dopaminergic activity in vivo
Sun, F., Zhou, J., Dai, B., Qian, T., Zeng, J., Li, X., Zhuo, Y., Zhang, Y., Wang, Y., Qian, C., Tan, K., Feng, J., Dong, H., Lin, D., Cui, G., Li, Y.
Nature Methods. 2020 Oct 21. [PDF] [BioRxiv version]
Neural mechanisms of aggression across species (Review)
Lischinsky, J.E., Lin, D.
Nature Neuroscience. 2020 Oct 12. [PDF]
Posterior amygdala regulates sexual and aggressive behaviors in male mice
Yamaguchi, T., Wei, D., Song, S.C., Lim, B., Tritsch, N.X., Lin, D.
Nature Neuroscience. 2020 July 27. [PDF]
Nilsson, S., Goodwin, N.L., Choong, J.J., Hwang, S., Wright, H. R., Norville, Z.C., Tong, X., Lin, D., Bentzley, B.S., Eshel, N., McLaughlin, R. J., Golden, S.A.
Hierarchical Representations of Aggression in a Hypothalamic-Midbrain Circuit
Falkner, A., Wei, D., Song, A., Watsek, L. W., Chen, I., Chen, P., Feng, J., Lin, D.
Neuron. 2020 Mar 11. [PDF] [Supplement] [BioRxiv version]
Neural circuits for coping with social defeat (Review)
Diaz, V., Lin, D.
Current Opinion in Neurobiology. 2020 Feb. [PDF]
2019
A Genetically Encoded Fluorescent Sensor for Rapid and Specific In Vivo Detection of Norepinephrine
Feng, J., Zhang, C., Lischinsky, J., Jing, M., Zhou, J., Wang, H., Zhang, Y., Dong, A., Wu, Z., Wu, H., Chen, W., Zhang, P., Zou, J., Hires, A., Zhu, J.J., Cui, G., Lin, D., Du, J., Li, Y.
Neuron. 2019 Mar 25. [PDF] [Supplement] [BioRxiv version]
Rapid, biphasic CRF neuronal responses encode positive and negative valence
Kim, J., Lee, S., Fang, Y., Shin, A., Park, S., Hashikawa, K., Bhat, S., Kim, D., Sohn, J.W., Lin, D., Suh, G.S.B.
Nature Neuroscience. 2019 Mar 4. [PDF] [Supplement] [BioRxiv version]
Hypothalamic Control of Conspecific Self-Defense
Wang, L., Talwar, V., Osakada, T., Kuang, A., Guo, Z., Yamaguchi, T., Lin, D.
Cell Reports. 2019 Feb 12. [PDF] [Supplement]
2018
The Neural Mechanisms of Sexually Dimorphic Aggressive Behaviors (Review)
Hashikawa, K., Hashikawa, Y., Lischinsky, J., Lin, D.
Trends in Genetics. 2018 August 30. [PDF]
Sun, F., Zeng, J., Jing, M., Zhou, J., Feng, J., Owen, S. F., Luo, Y., Li, F., Wang, H., Yamaguchi, T., Yong, Z., Gao, Y., Peng, W., Wang, L., Zhang, S., Du, J., Lin, D., Xu, M., Kreitzer, A. C., Cui, G., Li, Y.
Cell. 2018 July 12. [PDF] [Supplement] [BioRxiv version]
Functions of medial hypothalamic and mesolimbic dopamine circuitries in aggression (Review)
Yamaguchi, T., Lin, D.
Current Opinion In Behavioral Sciences. 2018 July 3. [PDF]
A Hypothalamic Midbrain Pathway Essential for Driving Maternal Behaviors
Fang, Y., Yamaguchi, T., Song, S.C., Tritsch, N.X., Lin, D.
Neuron. 2018 Apr 4. [PDF] [Supplement]
2017
Ventromedial Hypothalamus and the Generation of Aggression (Review)
Hashikawa, Y., Hashikawa, K., Falkner, A.L., Lin, D.
Frontiers in Systems Neuroscience. 2017 Dec 20. [PDF]
Esr1+ cells in the ventromedial hypothalamus control female aggression
Hashikawa, K., Hashikawa, Y., Tremblay, R., Zhang, J., Feng, J.E., Sabol, A., Piper, W.T., Lee, H., Rudy, B., Lin, D.
Nature Neuroscience. 2017 Sep 18. [PDF] [Supplement]
2016
Hypothalamic control of male aggression-seeking behavior
Falkner, A.L., Grosenick, L., Davidson, T.J., Deisseroth, K., Lin, D.
Nature Neuroscience. 2016 Apr;19(4):596-604. [PDF] [Supplement]
Effective modulation of male aggression through lateral septum to medial hypothalamus projection
Wong, L.C., Wang, L., D’amour, J.A., Yumita, T., Chen, G., Yamaguchi, T., Chang, B., Bernstein, H., You, X., Feng, J.E., Froemke, R.C., Lin, D.
Current Biology. 2016 Mar 7;26(5):593-604. [PDF] [Supplement]
The neural circuits of mating and fighting in male mice (Review)
Hashikawa, K., Hashikawa, Y., Falkner, A.L., Lin, D.
Current Opinion In Neurobiology. 2016 Jun; 38:27-37. [PDF]
2015
Collateral Pathways from the Ventromedial Hypothalamus Mediate Defensive Behaviors
Wang, L., Chen, I.Z., Lin, D.
Neuron. 2015 Mar 18;85(6):1344-58. [PDF] [Supplement]
2014
Recent advances in understanding the role of the hypothalamic circuit during aggression (Review)
Falkner, A.L., Lin, D.
Frontiers In Systems Neuroscience. 2014 Sep 25;8:168. [PDF]
Decoding ventromedial hypothalamic neural activity during male mouse aggression
Falkner, A.L., Dollar, P., Perona, P., Anderson, D.J., Lin, D.
Journal of Neuroscience. 2014 Apr 23;34(17):5971-84. [PDF]
Before
Functional identification of an aggression locus in the mouse hypothalamus
Lin, D., Boyle, M.P., Dollar, P., Lee, H., Perona, P., Lein, E.S., Anderson, D.J.
Nature. 2011 Feb 10;470(7333):221-6. [PDF]
Representation of natural stimuli in the mouse main olfactory bulb
Lin, D., Shea, S.D., Katz, L.C.
Neuron. 2006 Jun 15;50(6):937-49. [PDF] [Supplement]
Encoding social signals in the mouse main olfactory bulb
Lin, D., Zhang, S.Z., Block, E., Katz, L.C.
Nature. 2005 Mar 24;434(7032):470-7. [PDF]
Molecular determinants of synapsin targeting to presynaptic terminals
Gitler, D., Xu, Y., Kao, H.T., Lin, D., Lim, S., Feng, J., Greengard, P., Augustine, G.J.
Journal of Neuroscience. 2004 Apr 7;24(14):3711-20. [PDF]
Tang, G., Zhang, M., Xie, H., Jiang, S., Wang, Z., Xu, L., Hao, Y., Lin, D., Lan, H., Wang, Y,, Chen, L., Ren, D. (2002)
Neuroscience Letter. 2002 Aug 9;328(2):195-7.
Genetic study of apolipoprotein E gene, alpha-1 antichymotrypsin gene in sporadic Parkinson disease
Tang, G., Xie, H., Xu, L., Hao, Y., Lin, D., Ren, D.
Am J Med Genet. 2002 May 8;114(4):446-9.